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Neurofibromatosis from Head to Toe: What the Radio ...
RG210235-2022-Wang-SG
RG210235-2022-Wang-SG
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Pdf Summary
The study guide "Neurofibromatosis from Head to Toe: What the Radiologist Needs to Know" provides radiologists with key information about imaging features relevant to diagnosing neurofibromatosis. For neurofibromas, characteristic imaging appearances include peripheral enhancement on contrast-enhanced MRI, and a T2-hyperintense peripheral rim with a central hypointense component.<br /><br />In neurofibromatosis, focal areas of signal intensity (FASIs) in the brain may be depicted as isointense or mildly hyperintense on T1-weighted images. Additionally, a decreased or absent N-acetylaspartate level may be noted, which is a key metabolic feature. <br /><br />The guide also covers the most critical complications associated with neurofibromatosis types. In neurofibromatosis type 1 (NF1), malignant peripheral nerve sheath tumors (PNSTs) are the leading contributor to mortality. These malignant tumors may be suggested on MRI by large dimensions, central enhancement patterns, and surrounding cystic changes, all of which can differentiate them from benign neurofibromas.<br /><br />Regarding neurofibromatosis type 2 (NF2), it is frequently associated with meningiomas, which are another type of neurologic abnormality radiologists should be aware of when diagnosing and monitoring these patients. <br /><br />For further professional development and to earn continuing medical education credits, radiologists are directed to complete a related self-assessment activity online. This study guide is a preparatory resource designed to assist in the comprehension and identification of key imaging features associated with neurofibromatosis, enabling better diagnosis and patient management.
Keywords
neurofibromatosis
radiologist
neurofibromas
MRI
NF1
NF2
malignant peripheral nerve sheath tumors
meningiomas
imaging features
diagnosis
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