Manifestations of Sickle Cell Disorder at Abdominal and Pelvic Imaging. July-August 2022-RG210154-2022-Solomon-SG

RG210154-2022-Solomon-SG

Pdf Summary

The study guide for Test 210154 focuses on the manifestations of Sickle Cell Disorder (SCD) evident through abdominal and pelvic imaging. It provides a set of questions aimed at testing knowledge regarding the pathophysiology, complications, and imaging findings associated with SCD.<br /><br />1. <strong>Pathophysiologic Process</strong>: Sickle-shaped red blood cells develop due to the polymerization of mutated hemoglobin molecules, not due to genetic mutations of the α chain, oxygenized blood state, or changes in blood viscosity.<br /><br />2. <strong>Splenic Complication</strong>: Rapid enlargement of the spleen in individuals with SCD should raise suspicion for splenic sequestration, a common complication, rather than autosplenectomy, splenic infarct, or splenic petrification.<br /><br />3. <strong>Renal Papillary Necrosis Imaging</strong>: The imaging sign associated with renal papillary necrosis showing small irregular foci of contrast material pooling is identified as the lobster claw sign.<br /><br />4. <strong>Renal Mass Diagnosis</strong>: For a 41-year-old woman with sickle cell trait, the ultrasound findings suggest that the most likely diagnosis of a neoplasm is renal medullary carcinoma (RMC), as opposed to renal oncocytoma, renal cell carcinoma (clear cell), or renal abscess.<br /><br />5. <strong>Common Gallstone Type</strong>: Patients with SCD are most commonly affected by black pigment stones rather than cholesterol stones, struvite stones, or cystine stones.<br /><br />The study document serves as a supplementary educational tool, with additional resources and the opportunity to earn SA-CME credit accessible through the radiological society's online learning center. It's essential for medical professionals dealing with SCD to understand these imaging manifestations to make accurate diagnoses and manage the disorder effectively.

Keywords

Sickle Cell Disorder

abdominal imaging

pelvic imaging

pathophysiology

splenic sequestration

lobster claw sign

renal medullary carcinoma

black pigment stones

SA-CME credit

radiological society