Lesiones Hepáticas Inespecíficas: Un Enfoque Radiológico Actualizado (2026)-WEB0325-2026

Video Transcription

Video Summary

The webinar, hosted by RSNA, focused on the radiologic evaluation and management of indeterminate focal liver lesions from an up-to-date perspective. Dr. Guillermo Lizondo-Rioja opened with a review of liver-specific contrast agents, especially gadoxetic acid (Eovist/Primovist), explaining their hepatocyte uptake, biliary excretion, and value in dynamic and hepatobiliary phase MRI for distinguishing lesions with functional hepatocytes from those without them. He emphasized how these agents improve lesion detection, characterization, staging, and treatment planning.<br /><br />Dr. Fernando González then presented practical algorithms for managing indeterminate liver lesions, stressing that interpretation depends heavily on clinical context and malignancy risk. He reviewed typical benign patterns such as hemangioma and focal nodular hyperplasia, and highlighted suspicious features like ill-defined margins, heterogeneity, and diffusion restriction. Several case-based examples illustrated the importance of correlating imaging with symptoms and laboratory findings, including infectious and parasitic mimics, IgG4-related inflammatory pseudotumor, atypical focal nodular hyperplasia, and sclerosed hemangioma.<br /><br />A recurring theme was that many liver lesions are benign, and an atypical presentation of a common lesion is more likely than a rare diagnosis. When imaging is inconclusive, MRI, follow-up, or biopsy may be needed to avoid misdiagnosis and unnecessary surgery. The session ended with discussion of cirrhosis-related risk stratification (LI-RADS), metabolic liver disease, and the growing but still limited role of artificial intelligence in liver imaging.

Keywords

RSNA webinar

indeterminate focal liver lesions

radiologic evaluation

gadoxetic acid

Eovist Primovist

hepatobiliary phase MRI

liver lesion characterization

focal nodular hyperplasia

hemangioma

LI-RADS