Extraskeletal Ewing Sarcoma from Head to Toe: Multimodality Imaging Review. July-August 2022-RG210226-Elsayes-2022-SG

RG210226-Elsayes-2022-SG

Pdf Summary

This study guide is designed to assist medical professionals in preparing for the RadioGraphics Online SA-CME Test 210226, focusing on Extraskeletal Ewing Sarcoma (EES). The test examines knowledge about the imaging and pathology of EES. Participants can earn SA-CME credit upon completing the online test at rsna.org.<br /><br />1. Histopathologic Analysis: Ewing sarcoma family of tumors (ESFT) cells almost universally express strong membranous positivity for CD99. This finding, although consistent, is nonspecific.<br /><br />2. Imaging Characteristics of EES on MRI: Typically, EES demonstrates internal high T2-weighted signal intensity on MRI, corresponding to necrosis or cystic change.<br /><br />3. Imaging Appearance in Head and Neck Region: Extraskeletal Ewing sarcomas located extra-axially in the head and neck typically present as well-circumscribed lesions with avid enhancement on imaging studies.<br /><br />4. Common Sites in the Female Genital Tract: In females, the EES most frequently occurs in the vagina among other parts of the genital tract.<br /><br />5. Survival Rates Post-Chemotherapy: For patients with metastatic EES who have undergone cytotoxic chemotherapy, the 5-year survival rate is typically low, ranging from 15% to 32%.<br /><br />Medical professionals interested in gaining further insights into EES from head to toe are encouraged to fully review the study materials, utilizing multimodality imaging strategies to deepen understanding and improve diagnostic accuracy. As this guide is not eligible for SA-CME credit, remember to complete the official test online for accreditation.

Keywords

Extraskeletal Ewing Sarcoma

SA-CME Test

imaging pathology

CD99 expression

MRI characteristics

head and neck lesions

female genital tract

metastatic survival rates

cytotoxic chemotherapy

multimodality imaging